Objective: Ca2+ overload of muscle fibers is one of the factors that secondarily aggravate the development of Duchenne muscular dystrophy (DMD).The purpose of this study is to evaluate the effects of the Ca2+ channel modulator 2-aminoethoxydiphenyl borate (APB) on skeletal muscle pathology in dystrophin-deficient mdx mice.Methods: Mice were randoml
Even distribution of natural light is crucial in creating optimal visual comfort in classrooms.Many classrooms in tropical areas experience lighting imbalances, with areas near windows receiving excessive light, while others lack lighting.This study aims to evaluate the effectiveness of passive design strategies in improving the uniformity of natur
Cellular senescence entails essentially irreversible replicative arrest, apoptosis resistance, and frequently acquisition of a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP).Senescent cells accumulate in various tissues with aging and at sites of pathogenesis in many chronic diseases and conditions.The SASP ca
Global Positioning System technology has been widely used in vehicle tracking and road planning applications.An enormous amount of data concerning the trajectories of vehicles has been collected and stored for tracking purposes.A trajectory contains not only the footprints of a moving object but also additional information, such as speed and stoppi